Investing in the Future of NeuroTech

Nurturing early-stage innovation

The Nexus NeuroTech Incubator Program provides funding and support to promising early-stage companies developing breakthrough technologies for brain disorders.

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Addressing the funding gap in early-stage medtech

The conventional venture capital model, though effective for biotech, poses distinct challenges for early-stage medtech companies. Unlike therapeutics, medtech often lacks shorter-term exit opportunities, such as mergers and acquisitions following FDA Phase 2 success. Furthermore, the potential for substantial returns upon FDA Phase 3 success in therapeutics can make them a more appealing investment. Consequently, a funding gap emerges, where innovative neurotechnology companies or projects with promising scientific foundations but limited clinical evidence face difficulties in securing the capital needed for advancement.

The Nexus NeuroTech solution: a continuum of support

Nexus NeuroTech's Incubator Program aims to address this gap by employing a hybrid approach, combining aspects of both foundry/venture studio and pre-seed/seed investment models. This will enable us to support and invest in potentially transformative technologies that may not yet be ready for traditional venture capital.

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Incubator & Foundry Vertical

In this vertical, we create new companies based on promising intellectual property from our network of inventors and universities. These ventures will focus on advancing technologies aligned with Nexus NeuroTech’s strategic focus areas. The incubator will offer the necessary resources and expertise to drive these innovations through technical and clinical development, positioning them for pivotal trials and successful commercialization.

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Pre-seed & Seed Investment Vertical

In this vertical, we invest in pre-seed and seed-stage opportunities, supporting university spin-outs and startups that are developing neurotechnology solutions. These investments will align with Nexus NeuroTech’s strategic focus areas.

What we look for

The Nexus NeuroTech Incubator Program focuses on investing in technologies targeting Parkinson’s disease, autism spectrum disorder, and bipolar disorder, along with cross-cutting clinical areas such as seizures (common in autism spectrum disorder and elevated risk in Parkinson’s disease), cognitive dysfunction (common in Parkinson’s disease, autism spectrum disorder, and bipolar disorder), and mood disorders (common across autism spectrum disorder, Parkinson’s disease, and bipolar disorder) with:

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Promising scientific rationale but limited clinical evidence

  • Strong Theoretical Foundation
  • Preliminary Evidence
  • Plausible Mechanism of Action
  • Peer Validation
  • Acceptable Risk Assessment
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Pathway to de-risking and future investment

  • Prototype Development
  • Technical Proof of Concept (PoC)
  • Preclinical Testing (in vitro/in vivo)
  • Regulatory Pathway Identification
  • Intellectual Property Strategy
  • Early Market Validation
  • Team and Partnership Development Plans
  • Manufacturing Feasibility
  • Financial Milestones
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Alignment with the Nexus NeuroTech investment profile and beneficial ecosystem

  • Developing technologies with the potential to meaningfully improve patient outcomes. This might involve supporting companies that address underserved needs or explore novel approaches that complement existing Nexus NeuroTech initiatives.
  • Encouraging collaborations between incubator companies and other entities within the Nexus NeuroTech ecosystem, including research institutions, clinical centers, and existing portfolio companies. Such collaborations could involve data sharing, joint research projects, and early-stage validation studies, fostering a dynamic network of innovation within the ecosystem.
  • Supporting the development of research tools and platforms that can be broadly utilized within the ecosystem to accelerate discovery and clinical development.
  • Measuring the impact of incubator companies not solely through financial metrics, but also through their contributions to scientific advancements, patient access to novel therapies, and overall improvement in the quality of care.
Broader Ecosystem

Leveraging the Nexus NeuroTech ecosystem for success

Nexus NeuroTech is part of a broader ecosystem, which includes a number of leading organizations dedicated to advancing research and care for brain disorders. The incubator program will leverage the resources and expertise of our ecosystem to provide portfolio companies with access to:

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World-class clinical researchers and clinicians
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Rich datasets from clinical trials and patient registries
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Strategic guidance from industry leaders
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A network of potential investors, philanthropic donors, and partners
PROVIDED SUPPORT

How we support our incubator portfolio companies

Beyond capital, we offer a wide range of resources and support to help our portfolio companies succeed.

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Clinical Expertise and Support
  • Specialized Clinical Experts
  • Grant Proposal Support
  • Scientific Advisors and Key Opinion Leaders (KOLs)
  • Clinical Program Guidance
  • Scientific Diligence
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Technical Expertise and Support
  • Prototyping & Contract Manufacturing Support
  • Vendor Support
  • Product Development Expertise
  • Biomarker Expertise
  • Mechanical, Electrical, and Biomedical Engineering Experts
  • Professional Network
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Access to Rich Datasets
  • Technology-Enabled Platforms
  • Data Sharing Agreements
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Technical Expertise and Support
  • Technology-Enabled Solutions
  • Clinical Trial Infrastructure
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Financial Support
  • Pre-seed and Seed Funding
  • Philanthropic Funding
  • Co-investment from Other Institutions
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Pathway to Venture Funding
  • Transition to Nexus NeuroTech Venture Fund Investment
  • Preparation for Series A Funding

Want to reach out?

We welcome inquiries from company founders, academic investigators ready to commercialize their innovations, and investors who may wish to partner with us.

Contact us